Targeting Protein Tyrosine Phosphatases (PTPs) to enhance T cell immunotherapy

Investigating mechanisms for Elotuzumab and Lenalidomide therapy in Multiple Myeloma

Molecular and functional analysis of Mucinous Ovarian Carcinoma

Applications of massively parallel sequencing technology in the evaluation of haematological malignancies

The determinants of sensitivity and mechanism of action of eprenetapopt (APR-246)

Understanding the role of adenosine receptor signalling in chimeric antigen receptor (CAR) T cell therapy in solid cancer

Antimicrobials in hospitalised and high-risk children: understanding and improving use

Immunotherapy for Advanced Melanoma

Mechanisms regulating Drosophila neural stem cell proliferation

The control of lymphatic vascular remodelling in cancer by microRNAs

Clinical implications of genomic driver alterations in hormone receptor-positive, human epidermal growth factor receptor (HER) 2-negative early breast cancer

Targeting the Hippo pathway in malignant mesothelioma

The role of the MiT/TFE family of transcription factors in cytotoxic secretory granule formation in cytotoxic Tlymphocytes and the Niemann-Pick type C1 disease as a model

Investigating oncogenic FMS-like tyrosine kinase 3 (FLT3)-induced metabolic reprogramming in acute myeloid leukaemia

Investigating mechanisms of sensitivity and resistance to immunomodulatory thalidomide analogues in multiple myeloma

Pan-cancer reconstruction of clonal evolution in 1,800 patients using the discrete time-branching process

Circulating tumour DNA analysis for personalised care in breast cancer

Automated discovery of interacting genomic events that impact cancer survival by using data mining and machine learning techniques

Developing new therapies to treat advanced prostate cancer

Investigating the metabolic consequences resulting from the oncogenic activation of the PI3K-AKT pathway

Imaging and blood biomarkers: towards personalized medicine in head and neck cancer

Identification and Characterisation of the Cellular and Molecular Changes in Intestinal Metaplasia Associated with Progression to Gastric Cancer

CDK12 and CDK13 cooperatively regulate RNA polymerase II elongation and alternative polyadenylation of mRNA

Hippo pathway target genes and transcription factors in organ growth control

Novel biomarkers for melanoma immunotherapy

Examining the effects of BRAF, MEK and CDK4/6 inhibition on anti-tumor immunity in BRAFV600 melanoma

Transdifferentiation of cancer stem cells in brain tumours: Lessons from Drosophila neural stem cells

Coming of age with Li-Fraumeni syndrome: perspectives of young people and health professionals

Investigating drug response and resistance to IDH1R132H inhibition and hypomethylating agents in AML

Deciphering tumour heterogeneity in acute myeloid leukaemia at the single cell level

Enhancing CAR T cell therapy

Profiling the immune and genomic landscape of anal squamous cell carcinoma and establishing preclinical models to explore new therapeutic options

Harnessing senescence to control PI3K/AKT/mTORC pathway-driven cancer through the metabolic intervention

Study of the immunomodulatory effects of radiation therapy in solid cancers

Molecular regulation of adipogenesis in secondary lymphoedema: a common complication of cancer therapies

Understanding the clinical implications of the evolution of breast cancers from primary to metastatic disease using next generation sequencing