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ItemNo Preview AvailableNeuroimmune pathways regulating airway inflammation.Trevizan-Bau, P ; Mazzone, SB (Elsevier BV, 2023-07-29)Airways diseases are typically accompanied by inflammation, which has long been known to contribute to obstruction, mucus hypersecretion, dyspnea, cough, and other characteristic symptoms displayed in patients. Clinical interventions, therefore, often target inflammation to reverse lung pathology and reduce morbidity. The airways and lungs are densely innervated by subsets of nerve fibers, which are not only impacted by pulmonary inflammation but, in addition, likely serve as important regulators of immune cell function. This bidirectional neuroimmune crosstalk is supported by close spatial relationships between immune cells and airway nerve fibers, complementary neural and immune signaling pathways, local specialized airway chemosensory cells, and dedicated reflex circuits. In this article, we review the recent literature on this topic and present state-of-the-art evidence supporting the role of neuroimmune interactions in airway inflammation. In addition, we extend this evidence to synthesize considerations for the clinical translation of these discoveries to improve the management of patients with airway disease.
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ItemNo Preview AvailableNarrative Language and Literacy Education Research Within a Postcolonial FrameworkDoecke, B ; Anwar, D ; Illesca, B ; Mirhosseini, SA (SPRINGER INTERNATIONAL PUBLISHING AG, 2017)
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ItemNo Preview AvailableReflections on Qualitative Research in Language and Literacy EducationMirhosseini, S-A (Springer International Publishing, 2017)
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ItemNo Preview AvailableStepping Inside an English Classroom: Investigating the Everyday Experiences of an English TeacherBreen, L ; Illesca, B ; Doecke, B (ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, 2018-01-01)
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ItemNo Preview AvailableBeyond Measure: The Potential of Storytelling to Challenge Standardised EnglishIllesca, B (ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, )
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ItemWhat matters in the queer archive? Technologies of memory and Queering the MapWatson, A ; Kirby, E ; Churchill, B ; Robards, B ; LaRochelle, L (SAGE Publications, )Queering the Map ( queeringthemap.com ) is a novel digital platform: a storymap, an anonymous collaborative record, an archive of queer experiences. To contribute to the platform, visitors make their own mark by clicking on an empty space on the map. As to what visitors contribute, the platform’s About section suggests, simply, ‘If it counts for you, then it counts for Queering the Map’. In this article, we probe this guiding principle. What does count in this context? What matters in the queer archive? Drawing on interviews with 14 site users and an analysis of nearly 2000 stories pinned to Australia on the map, we consider what platform practices reveal about queer collective memory-making, to illuminate the how and why of a queer archive. We see that relatability matters because of the affective, affirming and community-building seeds it can generate; situation matters because it is through participatory practices that recognition, visibility and community place- making are enacted; and, the everyday matters as the archive’s visitors collectively claim and gift their varied personal experiences. Through these themes we explore queer contributions or how site visitors are oriented towards giving something of themselves to the archive. We discuss how archival properties of the platform are key to (queer) participation, and to meaning-making – as distinct, as queer, as a valued record. Queering the Map, we argue, is significant in how space is made for queer representation, carving new contours for archival ‘evidence’ and community histories.
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ItemMuscle Contributions to Take-Off Velocity in the Long JumpYang, K ; Tang, W-T ; Liu, S-H ; Pandy, MGG (LIPPINCOTT WILLIAMS & WILKINS, 2023-08)PURPOSE: A key determinant of long jump performance is the ability to increase the vertical velocity of the center of mass (COM) while minimizing the loss in forward velocity (running speed) during the take-off phase, but exactly how this occurs is not fully understood. We combined a three-dimensional musculoskeletal model of the body with dynamic optimization theory to simulate the biomechanics of the long jump take-off and determine the contributions of the individual leg muscles to jump performance. METHODS: The body was modeled as a 29-degree-of-freedom skeleton actuated by a combination of muscles and net joint torques. A dynamic optimization problem was solved to reproduce full-body motion and ground-force data recorded from experienced subelite jumpers. The optimization solution then was analyzed to determine each muscle's contribution to the ground-force impulse and hence the change in velocity of the COM during the take-off phase. RESULTS: The hip, knee, and ankle extensors dominated the change in velocity of the COM during take-off. Vasti (VAS) generated the highest support impulse and contributed one-third (33%) of the increase in vertical COM velocity generated by all the muscles. Soleus (SOL) and gluteus maximus (GMAX) also developed substantial support impulses and contributed 24% and 16% of the increase in vertical COM velocity, respectively. VAS also generated the highest braking impulse and contributed approximately one-half (55%) of the loss in forward COM velocity generated by all the muscles, whereas SOL and GMAX made much smaller contributions (12% and 7%, respectively). CONCLUSIONS: VAS, SOL, and GMAX contributed nearly three-quarters (73%) of the increase in vertical COM velocity at take-off, suggesting that these muscles ought to be prioritized in strength training programs aimed at improving long jump performance.
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ItemThe mental health of international university students from China during the COVID-19 pandemic and the protective effect of social support: A longitudinal studyKe, T ; Li, W ; Sanci, L ; Reavley, N ; Williams, I ; Russell, MA (ELSEVIER, 2023-02-16)BACKGROUND: During the COVID-19 pandemic Chinese international students were reported to experience racism, food security issues and social isolation. However, no study has investigated the prevalence of these issues and the potential for worsening mental health in this population group during the pandemic. Therefore, this study aimed to examine the effect of this pandemic on the mental health of Chinese international students living in Australia and China, and the protective effect of social support. METHODS: Data were extracted from a survey of Australian university students (April-June 2019) and follow-up during the pandemic (Sept-Oct 2020). The prevalence of anxiety, major depression and pandemic-related stressors was reported. Multivariable logistic regression was used to assess the association between country of residence, social support (baseline/follow-up), and follow-up self-reported mental health. RESULTS: With the pandemic, there was a substantial increase in the prevalence of anxiety (24.7 % vs 45.7 %) and major depression (22.1 % vs 43.8 %). Major depression was less likely to be reported by international students in China (34.8 %) than in Australia (46.3 %). Students with high social support during the pandemic were less likely to report major depression (Adjusted OR:0.15 [95 % CI 0.06,0.34]), although this effect was not observed longitudinally (Adjusted OR:1.03 [95 % CI 0.58,1.83]). LIMITATION: Post pandemic improvement in mental health cannot be assessed. CONCLUSION: The pandemic appeared to have had a strong negative effect on Chinese international university students' mental health. Those living in Australia were more likely to experience poorer mental health, highlighting the need for increased support to this group.
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ItemChanges in mental health across the COVID-19 pandemic for local and international university students in Australia: a cohort studyRussell, MA ; Reavley, N ; Williams, I ; Li, W ; Tarzia, L ; Chondros, P ; Sanci, L (SPRINGERNATURE, 2023-02-28)PURPOSE: Previous research has indicated that university students experienced substantial mental health issues during the global COVID-19 pandemic, but few studies have considered changes relative to pre-pandemic levels across population groups. Hence, the aim of this study was to compare changes in mental health and associated stressors across the pandemic for international and local university students studying in Australia. METHODS: In a cohort of 4407 university students, we assessed depression (Patient Health Questionnaire 2), anxiety (Generalized Anxiety Disorder-2), social support (Medical Outcomes Study-Social Support Survey), inability to afford food, fear of partner, and experiences of discrimination, both pre-pandemic (April-May 2019) and during the pandemic (September-October 2020). Change in prevalence between local and international students were estimated with logistic regression, adjusting for baseline factors. RESULTS: Compared to local students, international students experienced an increase in probable major depression (odds ratio (OR) 1.43, 95% Confidence Interval (CI) 1.23, 1.66), low social support (OR 2.63, 95% CI 2.23, 3.11), inability to afford food (OR 5.21, 95% CI 3.97, 6.83) race-based discrimination (OR 2.21, 95% CI 1.82, 2.68) and fear of partner (OR 3.46, 95% CI 2.26, 5.13). Interaction analyses indicated that these issues were more likely to be experienced by students living outside their country of origin, inclusive of international students based in Australia (depression p value interaction term 0.02). CONCLUSION: The pandemic had a substantial negative impact on international students, particularly those living outside of their country of origin during the pandemic. The inequalities exacerbated by the pandemic were present prior to the pandemic and are likely to continue post-pandemic without action. Interventions to build the supports for international students need to be urgently explored.
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ItemChanges in mental health across the COVID-19 pandemic for local and international university students in Australia: a cohort studyRussell, MA ; Reavley, N ; Williams, I ; Li, W ; Tarzia, L ; Chondros, P ; Sanci, L (SPRINGERNATURE, 2023-02-28)PURPOSE: Previous research has indicated that university students experienced substantial mental health issues during the global COVID-19 pandemic, but few studies have considered changes relative to pre-pandemic levels across population groups. Hence, the aim of this study was to compare changes in mental health and associated stressors across the pandemic for international and local university students studying in Australia. METHODS: In a cohort of 4407 university students, we assessed depression (Patient Health Questionnaire 2), anxiety (Generalized Anxiety Disorder-2), social support (Medical Outcomes Study-Social Support Survey), inability to afford food, fear of partner, and experiences of discrimination, both pre-pandemic (April-May 2019) and during the pandemic (September-October 2020). Change in prevalence between local and international students were estimated with logistic regression, adjusting for baseline factors. RESULTS: Compared to local students, international students experienced an increase in probable major depression (odds ratio (OR) 1.43, 95% Confidence Interval (CI) 1.23, 1.66), low social support (OR 2.63, 95% CI 2.23, 3.11), inability to afford food (OR 5.21, 95% CI 3.97, 6.83) race-based discrimination (OR 2.21, 95% CI 1.82, 2.68) and fear of partner (OR 3.46, 95% CI 2.26, 5.13). Interaction analyses indicated that these issues were more likely to be experienced by students living outside their country of origin, inclusive of international students based in Australia (depression p value interaction term 0.02). CONCLUSION: The pandemic had a substantial negative impact on international students, particularly those living outside of their country of origin during the pandemic. The inequalities exacerbated by the pandemic were present prior to the pandemic and are likely to continue post-pandemic without action. Interventions to build the supports for international students need to be urgently explored.