Medical Bionics - Research Publications
Now showing items 1-10 of 56
Peripheral injury of pelvic visceral sensory nerves alters GFR alpha (GDNF family receptor alpha) localization in sensory and autonomic pathways of the sacral spinal cord
(FRONTIERS MEDIA SA, 2015-04-10)
GDNF (glial cell line-derived neurotrophic factor), neurturin and artemin use their co-receptors (GFRα1, GFRα2 and GFRα3, respectively) and the tyrosine kinase Ret for downstream signaling. In rodent dorsal root ganglia ...
Are long stimulus pulse durations the answer to improving spatial resolution in retinal prostheses?
(AME PUBL CO, 2016-11-01)
Retinal prostheses can provide artificial vision to patients with degenerate retinae by electrically stimulating the remaining inner retinal neurons. The evoked perception is generally adequate for light localization, but ...
Viability of Long-Term Gene Therapy in the Cochlea
(NATURE PUBLISHING GROUP, 2014-04-22)
Gene therapy has been investigated as a way to introduce a variety of genes to treat neurological disorders. An important clinical consideration is its long-term effectiveness. This research aims to study the long-term ...
The Convergence of Cochlear Implantation with Induced Pluripotent Stem Cell Therapy
(HUMANA PRESS INC, 2012-09-01)
According to 2010 estimates from The National Institute on Deafness and other Communication Disorders, approximately 17% (36 million) American adults have reported some degree of hearing loss. Currently, the only clinical ...
Visual prostheses for the blind
(ELSEVIER SCIENCE LONDON, 2013-10-01)
After more than 40 years of research, visual prostheses are moving from the laboratory into the clinic. These devices are designed to provide prosthetic vision to the blind by stimulating localized neural populations in ...
'Like Pots and Pans Falling Down the Stairs'. Experience of Music Composed for Listeners with Cochlear Implants in a Live Concert Setting
(ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, 2014-06-01)
The acoustic and perceptual cues affecting melody segregation for listeners with a cochlear implant
(FRONTIERS MEDIA SA, 2013-11-06)
Our ability to listen selectively to single sound sources in complex auditory environments is termed "auditory stream segregation."This ability is affected by peripheral disorders such as hearing loss, as well as plasticity ...
Interhemispheric EEG coherence is reduced in auditory cortical regions in schizophrenia patients with auditory hallucinations
(ELSEVIER SCIENCE BV, 2013-07-01)
Central auditory processing has been reported to be impaired in schizophrenia patients who experience auditory hallucinations, and interhemispheric transfer in auditory circuits may be compromised. In this study, we used ...
Effects of chronic cochlear electrical stimulation after an extended period of profound deafness on primary auditory cortex organization in cats
Extended periods of deafness have profound effects on central auditory system function and organization. Neonatal deafening results in loss of the normal cochleotopic organization of the primary auditory cortex (AI), but ...
Effects of deafness and cochlear implant use on temporal response characteristics in cat primary auditory cortex
(ELSEVIER SCIENCE BV, 2014-09-01)
We have previously shown that neonatal deafness of 7-13 months duration leads to loss of cochleotopy in the primary auditory cortex (AI) that can be reversed by cochlear implant use. Here we describe the effects of a similar ...