Medical Bionics - Theses
Now showing items 1-9 of 9
Preclinical investigation of electrical field shaping strategies for retinal prostheses
Retinal prostheses are a promising technology aimed at restoring vision in people suffering severe retinal degenerative conditions such as retinitis pigmentosa (RP). Present-generation devices achieve this by electrically ...
Exploring the use of diamond in medical implants
Over recent decades, there is increasing interest in implantable devices that interact with neural tissue in the human body. Applications are broad, ranging from cardiac pacemakers to cochlear implants and beyond. The ...
Rate modulation and speech perception with cochlear implants
While cochlear implants (CI) have been successful in restoring a sense of hearing to people with severe to profound sensorineural hearing loss, there is still a wide variance in speech outcomes for CI users. Psychophysical ...
Language processing in cochlear implant users using fNIRS
Cochlear implant (CI) users differ in their auditory speech understanding ability. This variability is partly due to variability in deafness history and pathology, and partly due to functional brain changes that are likely ...
Prediction and shaping of visual cortex activity for retinal prostheses
Retinal prostheses are a promising treatment for blindness caused by photoreceptor degeneration. Electrodes implanted in the retina deliver electrical stimuli in the form of current pulses that activate surviving neurons ...
Investigating the effect of focused multipolar stimulation for cochlear implants: preclinical studies
Multichannel cochlear implants have been well accepted as an effective and safe treatment for severe to profound sensorineural hearing loss through electrical stimulation of residual spiral ganglion neurons. However, speech ...
Neural network models of pitch perception in normal and implanted ears
Pitch is the perceptual correlate of sound frequency and is important for using speech prosody, understanding tonal languages, and music appreciation. According to pitch perception theories, pitch is encoded by the place ...
Safety of a suprachoroidal retinal prosthesis
Light is transformed into neural signals by the retina. Certain conditions, such as retinitis pigmentosa, can cause extensive degeneration of the outer retinal layers, resulting in profound vision impairment. Prosthetic ...
Peripheral nerve stimulation for the treatment of chronic neuropathic pain
Neuropathic pain is a chronic health condition with a severe impact on the quality of life of affected patients. The condition is often difficult to manage and refractory to traditional pain treatment strategies such as ...