School of Biomedical Sciences - Research Publications
Now showing items 1-10 of 88
Differential expression of mesotocin receptors in the uterus and ovary of the pregnant tammar wallaby
(BIO SCIENTIFICA LTD, 2005-05-01)
Mesotocin, an oxytocin-like peptide, is released in highest concentrations during parturition in macropodid marsupials. In late pregnant wallabies, uterine sensitivity to mesotocin increases markedly in the myometrium of ...
Purification and characterization of relaxin from the tammar wallaby (Macropus eugenii): Bioactivity and expression in the corpus luteum
(SOC STUDY REPRODUCTION, 2002-07-01)
The objective of this study was to isolate and purify prorelaxin or mature relaxin from the tammar wallaby corpus luteum (CL), determine their structure and bioactivity, and test the hypothesis that enzymatic cleavage of ...
Up-regulation of mesotocin receptors in the tammar wallaby myometrium is pregnancy-specific and independent of estrogen
(SOC STUDY REPRODUCTION, 2002-05-01)
The oxytocin-like peptide of most Australian marsupials is mesotocin, which stimulates uterine contractions and is important for normal birth in the tammar wallaby. Female marsupials have two uteri and, in monovular species ...
PHOTOAFFINITY-LABELING OF CHLOROQUINE-BINDING PROTEINS IN PLASMODIUM-FALCIPARUM
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 1994-03-04)
A photoreactive analog of chloroquine, N-(4-(4-diethylamino-1-methylbutylamino)quinolin-6-yl)-4- azi do-2- hydroxybenzamide (referred to as ASA-Q), has been synthesized and shown to mimic the action of chloroquine in ...
Comparative Metabolomics of Mycoplasma bovis and Mycoplasma gallisepticum Reveals Fundamental Differences in Active Metabolic Pathways and Suggests Novel Gene Annotations
(AMER SOC MICROBIOLOGY, 2017-09-01)
Mycoplasmas are simple, but successful parasites that have the smallest genome of any free-living cell and are thought to have a highly streamlined cellular metabolism. Here, we have undertaken a detailed metabolomic ...
Skeletal Muscle Insulin Resistance Associated with Cholesterol-Induced Activation of Macrophages Is Prevented by High Density Lipoprotein
(PUBLIC LIBRARY SCIENCE, 2013-02-21)
BACKGROUND: Emerging evidence suggests that high density lipoprotein (HDL) may modulate glucose metabolism through multiple mechanisms including pancreatic insulin secretion as well as insulin-independent glucose uptake ...
Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis
(OXFORD UNIV PRESS, 2013-02-15)
Common diseases such as endometriosis (ED), Alzheimer's disease (AD) and multiple sclerosis (MS) account for a significant proportion of the health care burden in many countries. Genome-wide association studies (GWASs) for ...
Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips
(BIOMED CENTRAL LTD, 2011-03-08)
BACKGROUND: Illumina's Infinium SNP BeadChips are extensively used in both small and large-scale genetic studies. A fundamental step in any analysis is the processing of raw allele A and allele B intensities from each SNP ...
Multiple Sclerosis Susceptibility-Associated SNPs Do Not Influence Disease Severity Measures in a Cohort of Australian MS Patients
(PUBLIC LIBRARY SCIENCE, 2010-04-02)
Recent association studies in multiple sclerosis (MS) have identified and replicated several single nucleotide polymorphism (SNP) susceptibility loci including CLEC16A, IL2RA, IL7R, RPL5, CD58, CD40 and chromosome 12q13-14 ...
A Polymorphism in the HLA-DPB1 Gene Is Associated with Susceptibility to Multiple Sclerosis
(PUBLIC LIBRARY SCIENCE, 2010-10-26)
We conducted an association study across the human leukocyte antigen (HLA) complex to identify loci associated with multiple sclerosis (MS). Comparing 1927 SNPs in 1618 MS cases and 3413 controls of European ancestry, we ...