Melbourne School of Health Sciences Collected Works - Theses
Now showing items 1-9 of 9
The role of Dlk1 in haematopoiesis, leukaemia and angiogenesis
Delta-Like Homologue 1 (DLK1), also known as Preadipocyte Factor 1 (PREF-1), is a non-canonical EGF-like NOTCH ligand. It is maternally imprinted at the Dlk1-Dio3 imprinted locus, and has been shown to regulate embryonic ...
Swallowing difficulties in Friedreich ataxia
Swallowing is an important biological function reliant on the coordinated interaction between motor and sensory mechanisms. Swallowing dysfunction (dysphagia) is a common sequela of neurodegenerative disease and is ...
Toward relationship-centred care: patient-physiotherapist interaction in private practice
Interacting with patients is integral to the practice of physiotherapy. Notably, however, empirically derived knowledge about how physiotherapists interact with their patients is limited, particularly in the private practice ...
“I knew it was wrong but I couldn’t stop it”: young people talk about the prevention of sexually abusive behaviour
Child sexual abuse perpetrated by adults in family and institutional contexts is a well-known phenomenon. Child sexual abuse carried out by other children and young people, however, is a comparatively underexplored social ...
Active video game technologies for balance rehabilitation after stroke
Standing balance deficits are frequent and disabling following stroke; however, optimal assessment and treatment for balance problems remains unclear. The past decade has seen the increasing emergence and clinical uptake ...
Biomechanical and neuromuscular impairments in individuals with gluteal tendinopathy
Gluteal Tendinopathy (GT) is a typically chronic, recalcitrant cause of lateral hip pain most commonly seen in women aged 40 to 70 years. The condition involves pathology of the gluteus minimus and/or gluteus medius tendons ...
Corticomotor and biomechanical adaptations following anterior cruciate ligament rupture and reconstruction
This thesis examined neuromuscular and biomechanical adaptations associated with anterior cruciate ligament (ACL) rupture and reconstruction (ACLR). Studies utilized novel, non-invasive brain stimulation techniques to ...
Hip joint neuromuscular control and biomechanics in individuals with symptomatic femoroacetabular impingement
Femoroacetabular impingement (FAI) is recognised as a significant clinical problem among younger active adults. This morphological hip disorder can cause joint stiffness, hip and/or groin pain, and impaired function. ...
Construct Validity and Minimal Important Difference of 6-Minute Walk Distance in Survivors of Acute Respiratory Failure
(AMER COLL CHEST PHYSICIANS, 2015-05-01)
OBJECTIVE: The 6-min walk distance (6MWD), a widely used test of functional capacity, has limited evidence of construct validity among patients surviving acute respiratory failure (ARF) and ARDS. The objective of this study ...