A novel community driven software for functional enrichment analysis of extracellular vesicles data
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Editor
Date
2017-01-01
Source Title
Journal of Extracellular Vesicles
Publisher
TAYLOR & FRANCIS LTD
Melbourne Authors
Affiliation
Bio21
Sir Peter MacCallum Department of Oncology
Sir Peter MacCallum Department of Oncology
Document Type
Journal Article
Subject Code
Citations
Pathan, M., Keerthikumar, S., Chisanga, D., Alessandro, R., Ang, C. S., Askenase, P., Batagov, A. O., Benito-Martin, A., Camussi, G., Clayton, A., Collino, F., di Vizio, D., Falcon-Perez, J. M., Fonseca, P., Fonseka, P., Fontana, S., Gho, Y. S., Hendrix, A., Nolte-’T Hoen, E. ,... Mathivanan, S. (2017). A novel community driven software for functional enrichment analysis of extracellular vesicles data. Journal of Extracellular Vesicles, 6 (1), https://doi.org/10.1080/20013078.2017.1321455.
Access Status
Open Access
Access URL
Open Access URL
Open Access at PMC
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NHMRC Grant Code
ARC Grant Code
Description
Abstract
Bioinformatics tools are imperative for the in depth analysis of heterogeneous high-throughput data. Most of the software tools are developed by specific laboratories or groups or companies wherein they are designed to perform the required analysis for the group. However, such software tools may fail to capture "what the community needs in a tool". Here, we describe a novel community-driven approach to build a comprehensive functional enrichment analysis tool. Using the existing FunRich tool as a template, we invited researchers to request additional features and/or changes. Remarkably, with the enthusiastic participation of the community, we were able to implement 90% of the requested features. FunRich enables plugin for extracellular vesicles wherein users can download and analyse data from Vesiclepedia database. By involving researchers early through community needs software development, we believe that comprehensive analysis tools can be developed in various scientific disciplines.