Reduced orbitofrontal cortical thickness in male adolescents with internet addiction

Thumbnail Image
Citations
Web of Science:
69
Scopus:
79
Altmetric:
Altmetric::
Download
Published version (433.01 KB)
Associated Records
Authors
Hong, SB; Kim, JW; Choi, EJ; Kim, HH; Suh, JE; Kim, CD; Klauser, P; Whittle, S; Yucel, M; Pantelis, C...
File Licence
Editors
Date
2013-03-12
Source Title
Behavioral and Brain Functions
Journal Title
Journal ISSN
Volume Title
Publisher
BIOMED CENTRAL LTD
Melbourne Authors
Pantelis, Christos ORCID
 Whittle, Sarah ORCID
 Yucel, Murat
HONG, SOONBUM
Klauser, Paul ORCID
Affiliation
Psychiatry
Document Type
Journal Article
Subject Code
Citation
Hong, S. B., Kim, J. W., Choi, E. J., Kim, H. H., Suh, J. E., Kim, C. D., Klauser, P., Whittle, S., Yucel, M., Pantelis, C. & Yi, S. H. (2013). Reduced orbitofrontal cortical thickness in male adolescents with internet addiction. Behavioral and Brain Functions, 9 (1), https://doi.org/10.1186/1744-9081-9-11.
Access Status
Open Access
URI
https://hdl.handle.net/11343/41979
DOI
10.1186/1744-9081-9-11
Access URL
Open Access URL
Open Access at PMC
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608995
Linked Resource URL
NHMRC Grant Code
NHMRC/1021973
ARC Grant Code
Description
Abstract
BACKGROUND: The orbitofrontal cortex (OFC) has consistently been implicated in the pathology of both drug and behavioral addictions. However, no study to date has examined OFC thickness in internet addiction. In the current study, we investigated the existence of differences in cortical thickness of the OFC in adolescents with internet addiction. On the basis of recently proposed theoretical models of addiction, we predicted a reduction of thickness in the OFC of internet addicted individuals. FINDINGS: Participants were 15 male adolescents diagnosed as having internet addiction and 15 male healthy comparison subjects. Brain magnetic resonance images were acquired on a 3T MRI and group differences in cortical thickness were analyzed using FreeSurfer. Our results confirmed that male adolescents with internet addiction have significantly decreased cortical thickness in the right lateral OFC (p<0.05). CONCLUSION: This finding supports the view that the OFC alterations in adolescents with internet addiction reflect a shared neurobiological marker of addiction-related disorders in general.
Notes
Terms of Use
Keywords
CORTEX, DISORDERS, INVOLVEMENT, CHILDREN, CORTEX, DISORDERS, INVOLVEMENT, CHILDREN
Publisher Licence
CC BY
Publisher URL
https://doi.org/10.1186/1744-9081-9-11
Collections
Psychiatry - Research Publications
Minerva Elements Records