Polyspecific intravenous immunoglobulin in clindamycin-treated patients with streptococcal toxic shock syndrome: A systematic review and meta-analysis
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2018-10-15
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Clinical Infectious Diseases
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OXFORD UNIV PRESS INC
Melbourne Authors
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Paediatrics (RCH)
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Journal Article
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Parks, T., Wilson, C., Curtis, N., Norrby-Teglund, A. & Sriskandan, S. (2018). Polyspecific intravenous immunoglobulin in clindamycin-treated patients with streptococcal toxic shock syndrome: A systematic review and meta-analysis. Clinical Infectious Diseases, 67 (9), pp.1434-1436. https://doi.org/10.1093/cid/ciy401.
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Abstract
We evaluated the effect of intravenous immunoglobulin (IVIG) on mortality in clindamycin-treated streptococcal toxic shock syndrome using a meta-analysis. In association with IVIG, mortality fell from 33.7% to 15.7% with remarkable consistency across the single randomized and four nonrandomized studies.