TY  - JOUR
AU  - Jamadar, SD
AU  - Ward, PGD
AU  - Close, TG
AU  - Fornito, A
AU  - Premaratne, M
AU  - O'Brien, K
AU  - Stab, D
AU  - Chen, Z
AU  - Shah, NJ
AU  - Egan, GF
Y2  - 2020/11/17
Y1  - 2020/10/21
SN  - 2052-4463
UR  - http://hdl.handle.net/11343/251742
AB  - Simultaneous [18 F]-fluorodeoxyglucose positron emission tomography and functional magnetic resonance imaging (FDG-PET/fMRI) provides the capability to image two sources of energetic dynamics in the brain - cerebral glucose uptake and the cerebrovascular haemodynamic response. Resting-state fMRI connectivity has been enormously useful for characterising interactions between distributed brain regions in humans. Metabolic connectivity has recently emerged as a complementary measure to investigate brain network dynamics. Functional PET (fPET) is a new approach for measuring FDG uptake with high temporal resolution and has recently shown promise for assessing the dynamics of neural metabolism. Simultaneous fMRI/fPET is a relatively new hybrid imaging modality, with only a few biomedical imaging research facilities able to acquire FDG PET and BOLD fMRI data simultaneously. We present data for n = 27 healthy young adults (18-20 yrs) who underwent a 95-min simultaneous fMRI/fPET scan while resting with their eyes open. This dataset provides significant re-use value to understand the neural dynamics of glucose metabolism and the haemodynamic response, the synchrony, and interaction between these measures, and the development of new single- and multi-modality image preparation and analysis procedures.
LA  - English
PB  - NATURE RESEARCH
T1  - Simultaneous BOLD-fMRI and constant infusion FDG-PET data of the resting human brain
DO  - 10.1038/s41597-020-00699-5
IS  - Scientific Data
VL  - 7
IS  - 1
SP  - 363-
L1  - /bitstream/handle/11343/251742/PMC7578808.pdf?sequence=1&isAllowed=y
ER  -