TY  - JOUR
AU  - Dowsey, MM
AU  - Gould, D
AU  - Spelman, T
AU  - Pandy, MG
AU  - Choong, PF
Y2  - 2020/11/27
Y1  - 2020/06
SN  - 0883-5403
UR  - http://hdl.handle.net/11343/252325
AB  - Background
The purpose of this randomized controlled trial was to compare the performance of 3 total knee joint replacement (TKJR) designs 6 months after the surgery.

Methods
Patients were recruited between March 2015 and March 2018. Patients with osteoarthritis consented for TKJR were randomly allocated to a medial stabilized (MS), cruciate retaining (CR), or posterior stabilized (PS) design. Primary outcome measures were self-reported improvement in pain and function 6 months after TKJR, using the Oxford Knee Score. Secondary outcome measures were the Western Ontario and McMaster Universities Osteoarthritis Index, Veterans RAND 12-item Health Survey, Knee Society Score 2011, Timed Up and Go test, and Six-Minute Walk Test. Twelve-month outcomes were also measured.

Results
Ninety participants enrolled, 83 were randomized: PS (n = 26), CR (n = 28), and MS (n = 29) designs. One case withdrew before surgery: planned use of non-study implant; 7 did not complete all outcome measures. No 6-month between-group difference was observed for the primary outcome. A 6-month difference was observed in Knee Society Score 2011 Satisfaction: MS favored over CR and PS. Clinically meaningful 12-month differences in Western Ontario and McMaster Universities Osteoarthritis Index Pain, Function, and Global Subscales were observed: MS favored over CR. Twelve-month differences occurred in Veterans RAND 12-item Health Survey mental well-being, favoring MS and PS over CR.

Conclusion
MS prosthesis can be expected to yield similar clinical and functional outcomes to PS and CR designs 6 months after TKJR, and patients were more satisfied with their outcome. Compared with CR, patients with MS prosthesis also reported superior pain, function, and quality-of-life outcomes at 12 months.
LA  - en
PB  - Elsevier BV
T1  - A Randomized Controlled Trial Comparing a Medial Stabilised Total Knee Prosthesis to a Cruciate Retaining and Posterior Stabilised Design - A Report of the Clinical and Functional Outcomes Following Total Knee Replacement
DO  - 10.1016/j.arth.2020.01.085
IS  - Journal of Arthroplasty
VL  - 35
IS  - 6
SP  - 1583-1590
OP  - 1122526
OP  - 1154203
L1  - /bitstream/handle/11343/252325/PIIS0883540320301224.pdf?sequence=1&isAllowed=y
ER  -