TY  - JOUR
AU  - Rogers, GB
AU  - Kozlowska, J
AU  - Keeble, J
AU  - Metcalfe, K
AU  - Fao, M
AU  - Dowd, SE
AU  - Mason, AJ
AU  - McGuckin, MA
AU  - Bruce, KD
Y2  - 2020/12/18
Y1  - 2014/06/25
SN  - 2045-2322
UR  - http://hdl.handle.net/11343/255563
AB  - Despite the fundamental contribution of the gut microbiota to host physiology, the extent of its variation in genetically-identical animals used in research is not known. We report significant divergence in both the composition and metabolism of gut microbiota in genetically-identical adult C57BL/6 mice housed in separate controlled units within a single commercial production facility. The reported divergence in gut microbiota has the potential to confound experimental studies using mammalian models.
LA  - English
PB  - NATURE PUBLISHING GROUP
T1  - Functional divergence in gastrointestinal microbiota in physically-separated genetically identical mice
DO  - 10.1038/srep05437
IS  - Scientific Reports
VL  - 4
IS  - 1
L1  - /bitstream/handle/11343/255563/PMC4069701.pdf?sequence=1&isAllowed=y
ER  -