TY  - JOUR
AU  - Dagley, MJ
AU  - McConville, MJ
Y2  - 2020/12/18
Y1  - 2018/06/01
SN  - 1367-4803
UR  - http://hdl.handle.net/11343/255999
AB  - Summary: Stable isotope directed metabolomics is increasingly being used to measure metabolic fluxes in microbial, plant and animal cells. Incorporation of 13C/15N isotopes into a wide range of metabolites is typically determined using gas chromatography-mass spectrometry (GC/MS) or other hyphenated mass spectrometry approaches. The DExSI (Data Extraction for Stable Isotope-labelled metabolites) pipeline is an interactive graphical software package which can be used to rapidly quantitate isotopologues for a wide variety of metabolites detected by GC/MS. DExSI performs automated metabolite annotation, mass and positional isotopomer abundance determination and natural isotope abundance correction. It provides a range of output options and is suitable for high throughput analyses. Availability and implementation: DExSI is available for non-commercial use from: https://github.com/DExSI/DExSI/. For Microsoft Windows 7 or higher (64-bit). Contact: malcolmm@unimelb.edu.au or michael.dagley@unimelb.edu.au. Supplementary information: Supplementary data are available at Bioinformatics online.
LA  - English
PB  - OXFORD UNIV PRESS
T1  - DExSI: a new tool for the rapid quantitation of C-13-labelled metabolites detected by GC-MS
DO  - 10.1093/bioinformatics/bty025
IS  - Bioinformatics
VL  - 34
IS  - 11
SP  - 1957-1958
L1  - /bitstream/handle/11343/255999/PMC5972663.pdf?sequence=1&isAllowed=y
ER  -