TY  - JOUR
AU  - Shehata, HM
AU  - Murphy, AJ
AU  - Lee, MKS
AU  - Gardiner, CM
AU  - Crowe, SM
AU  - Sanjabi, S
AU  - Finlay, DK
AU  - Palmer, CS
Y2  - 2020/12/21
Y1  - 2017/10/16
SN  - 1664-3224
UR  - http://hdl.handle.net/11343/257394
AB  - The realization that an intricate link exists between the metabolic state of immune cells and the nature of the elicited immune responses has brought a dramatic evolution to the field of immunology. We will focus on how metabolic reprogramming through the use of glycolysis and fatty-acid oxidation (sugar or fat) regulates the capacity of immune cells to mount robust and effective immune responses. We will also discuss how fine-tuning sugar and fat metabolism may be exploited as a novel immunotherapeutic strategy to fight viral infections or improve vaccine efficacy.
LA  - English
PB  - FRONTIERS MEDIA SA
T1  - Sugar or Fat? - Metabolic Requirements for Immunity to Viral Infections
DO  - 10.3389/fimmu.2017.01311
IS  - Frontiers in Immunology
VL  - 8
IS  - OCT
L1  - /bitstream/handle/11343/257394/PMC5649203.pdf?sequence=1&isAllowed=y
ER  -