TY  - JOUR
AU  - Mack, HG
AU  - Tien, MC-H
AU  - White, OB
Y2  - 2020/12/22
Y1  - 2016/09/01
SN  - 1663-2699
UR  - http://hdl.handle.net/11343/258092
AB  - Fingolimod is an oral sphingosine-1-phosphate (S1P) receptor modulator and the first oral therapy for relapsing-remitting multiple sclerosis. Its use has been complicated by a low rate of cystoid macular edema usually in the first 3 months after commencement of the medication. We report the case of a 34-year-old male with relapsing-remitting multiple sclerosis, who developed acute anterior uveitis on day 5 of fingolimod treatment. He responded to appropriate treatment and cessation of drug, but developed low-grade chronic anterior uveitis without cystoid macular edema. We discuss possible mechanisms of uveitis onset in this group of patients. Urgent ophthalmological review is recommended for patients receiving fingolimod therapy who develop a red, painful eye, which may occur within 5 days of fingolimod treatment initiation.
LA  - English
PB  - KARGER
T1  - Acute Anterior Uveitis in a Patient Taking Fingolimod (FTY720) for Multiple Sclerosis
DO  - 10.1159/000453392
IS  - Case Reports in Ophthalmology
VL  - 7
IS  - 3
SP  - 284-288
L1  - /bitstream/handle/11343/258092/PMC5216206.pdf?sequence=1&isAllowed=y
ER  -