TY  - JOUR
AU  - Tai, ELM
AU  - Li, L-J
AU  - Wan-Hazabbah, WH
AU  - Wong, T-Y
AU  - Shatriah, I
Y2  - 2020/12/22
Y1  - 2017/01/20
SN  - 1932-6203
UR  - http://hdl.handle.net/11343/258104
AB  - PURPOSE: Retinal vessel analysis is affected by both systemic and ocular factors. Malays are the major ethnicity in South East Asia. Data on the retinal microvasculature in Malays is limited, especially among children. We aim to evaluate the influence of ocular biometry on retinal vessel parameters in young Malay girls. METHODS: This was a cross-sectional, hospital-based study involving 86 Malay girls aged 6 to 12 years old in Hospital Universiti Sains Malaysia from 2015-2016. Ocular examination, refraction, biometry, retinal photography, and anthropometric measurements were performed. The central retinal arteriolar equivalent (CRAE), central retinal venular equivalent (CRVE) and overall fractal dimension (Df) were measured using validated computer-based methods (Singapore I vessel analyzer, SIVA version 3.0, Singapore). The associations of ocular biometry and CRAE, CRVE and Df were analyzed using multivariable analysis. RESULTS: The mean CRAE, CRVE and Df in Malay girls were 171.40 (14.40) um, 248.02 (16.95) um and 1.42 (0.05) respectively. Each 1 mm increase in axial length was associated with a reduction of 4.25 um in the CRAE (p = 0.03) and a reduction of 0.02 in the Df (p = 0.02), after adjustment for age, blood pressure and body mass index. No association was observed between axial length and CRVE. Anterior chamber depth and corneal curvature had no association with CRAE, CRVE or Df. CONCLUSION: Axial length affects retinal vessel measurements. Narrower retinal arterioles and reduced retinal fractal dimension were observed in Malay girls with longer axial lengths.
LA  - English
PB  - PUBLIC LIBRARY SCIENCE
T1  - Effect of Axial Eye Length on Retinal Vessel Parameters in 6 to 12-Year-Old Malay Girls
DO  - 10.1371/journal.pone.0170014
IS  - PLoS One
VL  - 12
IS  - 1
L1  - /bitstream/handle/11343/258104/PMC5249240.pdf?sequence=1&isAllowed=y
ER  -