TY  - JOUR
AU  - Sachdev, PS
AU  - Lipnicki, DM
AU  - Kochan, NA
AU  - Crawford, JD
AU  - Thalamuthu, A
AU  - Andrews, G
AU  - Brayne, C
AU  - Matthews, FE
AU  - Stephan, BCM
AU  - Lipton, RB
AU  - Katz, MJ
AU  - Ritchie, K
AU  - Carriere, I
AU  - Ancelin, M-L
AU  - Lam, LCW
AU  - Wong, CHY
AU  - Fung, AWT
AU  - Guaita, A
AU  - Vaccaro, R
AU  - Davin, A
AU  - Ganguli, M
AU  - Dodge, H
AU  - Hughes, T
AU  - Anstey, KJ
AU  - Cherbuin, N
AU  - Butterworth, P
AU  - Ng, TP
AU  - Gao, Q
AU  - Reppermund, S
AU  - Brodaty, H
AU  - Schupf, N
AU  - Manly, J
AU  - Stern, Y
AU  - Lobo, A
AU  - Lopez-Anton, R
AU  - Santabarbara, J
Y2  - 2020/12/22
Y1  - 2015/11/05
SN  - 1932-6203
UR  - http://hdl.handle.net/11343/258170
AB  - BACKGROUND: Changes in criteria and differences in populations studied and methodology have produced a wide range of prevalence estimates for mild cognitive impairment (MCI). METHODS: Uniform criteria were applied to harmonized data from 11 studies from USA, Europe, Asia and Australia, and MCI prevalence estimates determined using three separate definitions of cognitive impairment. RESULTS: The published range of MCI prevalence estimates was 5.0%-36.7%. This was reduced with all cognitive impairment definitions: performance in the bottom 6.681% (3.2%-10.8%); Clinical Dementia Rating of 0.5 (1.8%-14.9%); Mini-Mental State Examination score of 24-27 (2.1%-20.7%). Prevalences using the first definition were 5.9% overall, and increased with age (P < .001) but were unaffected by sex or the main races/ethnicities investigated (Whites and Chinese). Not completing high school increased the likelihood of MCI (P ≤ .01). CONCLUSION: Applying uniform criteria to harmonized data greatly reduced the variation in MCI prevalence internationally.
LA  - English
PB  - PUBLIC LIBRARY SCIENCE
T1  - The Prevalence of Mild Cognitive Impairment in Diverse Geographical and Ethnocultural Regions: The COSMIC Collaboration
DO  - 10.1371/journal.pone.0142388
IS  - PLoS One
VL  - 10
IS  - 11
L1  - /bitstream/handle/11343/258170/PMC4634954.pdf?sequence=1&isAllowed=y
ER  -