TY  - JOUR
AU  - Onofrillo, C
AU  - Galbiati, A
AU  - Montanaro, L
AU  - Derenzini, M
Y2  - 2020/12/22
Y1  - 2017/01/17
SN  - 1949-2553
UR  - http://hdl.handle.net/11343/258203
AB  - Pre-ribosomal complex RPL5/RPL11/5S rRNA (5S RNP) is considered the central MDM2 inhibitory complex that control p53 stabilization during ribosome biogenesis inhibition. Despite its role is well defined, the dynamic of 5S RNP assembly still requires further characterization. In the present work, we report that MDM2 inhibition is dependent by a pre-existing population of 5S rRNA.
LA  - English
PB  - IMPACT JOURNALS LLC
T1  - The pre-existing population of 5S rRNA effects p53 stabilization during ribosome biogenesis inhibition
DO  - 10.18632/oncotarget.13833
IS  - Oncotarget
VL  - 8
IS  - 3
SP  - 4257-4267
L1  - /bitstream/handle/11343/258203/PMC5354829.pdf?sequence=1&isAllowed=y
ER  -