TY  - JOUR
AU  - SINNOTT, RICHARD
AU  - STELL, ANTHONY
AU  - Ajayi, Oluwafemi
Y2  - 2014/05/21
Y1  - 2006
UR  - http://hdl.handle.net/11343/28868
AB  - E-Health initiatives such as electronic clinical trials and epidemiological studies require access to and usage of a range of both clinical and other data sets. Such data sets are typically only available over many heterogeneous domains where a plethora of often legacy based or in-house/bespoke IT solutions exist. Considerable efforts and investments are being made across the UK to upgrade the IT infrastructures across the National Health Service (NHS) such as the National Program for IT in the NHS (NPFIT) [1]. However, it is the case that currently independent and largely non-interoperable IT solutions exist across hospitals, trusts, disease registries and GP practices – this includes security as well as more general compute and data infrastructures. Grid technology allows issues of distribution and heterogeneity to be overcome, however the clinical trials domain places special demands on security and data which hitherto the Grid community have not satisfactorily addressed. These challenges are often common across many studies and trials hence the development of a re-usable framework for creation and subsequent management of such infrastructures is highly desirable. In this paper we present the challenges in developing such a framework and outline initial scenarios and prototypes developed within the MRC funded Virtual Organisations for Trials and Epidemiological Studies (VOTES) project [2].
LA  - eng
PB  - IOS Press
KW  - clinical trials
KW  - Grid technology
T1  - Development of grid frameworks for clinical trials and epidemiological studies
IS  - Studies in Health Technology and Informatics
VL  - 120
SP  - 117-130
L1  - /bitstream/handle/11343/28868/264231_7318.pdf?sequence=1&isAllowed=y
ER  -