TY  - GEN
AU  - Weih, LeAnn M.
AU  - Mukesh, Nanjan
AU  - McCarty, Catherine A.
AU  - Taylor, Hugh R.
Y2  - 2014/05/22
Y1  - 2001/11
UR  - http://hdl.handle.net/11343/33489
AB  - Purpose: To determine the prevalence and investigate predictors of open-angle glaucoma in Victoria, Australia
                        
                    Design: Two-site, population-based cross-sectional study.
                        
                    Participants: Permanent residents aged 40 years and older at recruitment from 1992 through 1996.
                        
                    Methods: A cluster-stratified random sample of 4744 participants from two cohorts, urban and rural, participated. Participants completed a standardized interview regarding demographic, lifestyle, and medical characteristics and a dilated eye examination including measurement of intraocular pressure, visual fields, cup-to-disc ratios, and paired stereo photography of the optic discs. A consensus panel of six ophthalmologists determined glaucoma diagnosis.
                        
                    Main Outcome Measure: Diagnosis of glaucoma (possible, probable, definite).
                        
                    Results: The prevalence of possible glaucoma cases was 1.2% (95% confidence interval [CI], 0.60, 1.7), of probable cases was 0.70% (95% CI, 0.39, 1.0), and of definite cases was 1.8% (95% CI, 1.4, 2.2). There was a significant increase in glaucoma prevalence with age across all definitions, but there was no difference in age-standardized rates between genders. A total of 60% of probable and definite glaucoma cases were undiagnosed before this study. Adjusted for age, the strongest risk factor for glaucoma was a positive family history of glaucoma (odds ratio, 3.1; 95% CI, 1.6, 5.3). Glaucoma patients who had not attended an eye care provider in the last 2 years were eight times (95% CI, 3.2, 20.4) more likely to have undiagnosed disease.
                        
                    Conclusions: These results support the importance of the genetic or familial basis of many glaucoma cases and highlight the need to develop appropriate techniques to screen for undiagnosed disease.
N1  - application/pdf
LA  - eng
PB  - Elsevier (American Academy of Ophthalmology)
KW  - CERA
KW  - ophthalmology
KW  - Centre for Eye Research Australia
KW  - eye research
KW  - vision
KW  - visual health
KW  - glaucoma
T1  - Prevalence and predictors of open-angle glaucoma : results from the Visual Impairment Project
IS  - Ophthalmology
VL  - 108
IS  - 11
SP  - 1966-1972
L1  - /bitstream/handle/11343/33489/65581_00002752_01_preval~1.pdf?sequence=1&isAllowed=n
ER  -